UK Biobank retinal imaging grading: methodology, baseline characteristics and findings for common ocular diseases.

ABSTRACT:

Background/objectives

This study aims to describe the grading methods and baseline characteristics for UK Biobank (UKBB) participants who underwent retinal imaging in 2009-2010, and to characterise individuals with retinal features suggestive of age-related macular degeneration (AMD), glaucoma and retinopathy.

Methods

Non-mydriatic colour fundus photographs and macular optical coherence tomography (OCT) scans were manually graded by Central Administrative Research Facility certified graders and quality assured by clinicians of the Network of Ophthalmic Reading Centres UK. Captured retinal features included those associated with AMD (≥1 drusen, pigmentary changes, geographic atrophy or exudative AMD; either imaging modality), glaucoma (≥0.7 cup-disc ratio, ≥0.2 cup-disc ratio

SUBMITTER: Warwick AN 

PROVIDER: S-EPMC10333328 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature