Patient-reported outcomes in refractory hormone-producing pituitary adenomas: an unmet need.

ABSTRACT:

Purpose

To describe quality and outcomes of patient-reported outcome (PRO) measures (PROMs) used in patients with refractory hormone-producing pituitary adenomas, and to provide an overview of PROs in these challenging pituitary adenomas.

Methods

Three databases were searched for studies reporting on refractory pituitary adenomas. For the purpose of this review, refractory adenomas were defined as tumors resistant to primary therapy. General risk of bias was assessed using a component approach and the quality of PROM reporting was assessed using the International Society for Quality of Life Research (ISOQOL) criteria.

Results

20 studies reported on PROMs in refractory pituitary adenomas, using 14 different PROMs, of which 4 were disease specific (median general risk o

SUBMITTER: van Trigt VR 

PROVIDER: S-EPMC10333395 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature