Serum copper levels and risk of major adverse cardiovascular events: a systematic review and meta-analysis.

ABSTRACT:

Background

Despite the fact that several studies have investigated the association between serum copper levels (S-Cu) and the risk of cardiovascular diseases, this relationship remains unclear. The aims of this study were to investigate the association between S-Cu and risk of major adverse cardiovascular events (MACE), including total stroke, ischemic stroke, hemorrhagic stroke, myocardial infarction and cardiovascular mortality, and identify potential sources of results heterogeneity.

Methods

We carried out a systematic review and meta-analysis. The selection criteria were: (1) Observational studies (cohort studies, case-control studies and hybrid studies); (2) Studies containing quantitative data about the relationship between S-Cu and risk of MACE; (3) Estimating associa

SUBMITTER: Munoz-Bravo C 

PROVIDER: S-EPMC10333529 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature