Bilateral lung transplantation for pediatric pulmonary arterial hypertension: perioperative management and one-year follow-up.

ABSTRACT:

Background

Bilateral lung transplantation (LuTx) remains the only established treatment for children with end-stage pulmonary arterial hypertension (PAH). Although PAH is the second most common indication for LuTx, little is known about optimal perioperative management and midterm clinical outcomes.

Methods

Prospective observational study on consecutive children with PAH who underwent LuTx with scheduled postoperative VA-ECMO support at Hannover Medical School from December 2013 to June 2020.

Results

Twelve patients with PAH underwent LuTx (mean age 11.9 years; age range 1.9-17.8). Underlying diagnoses included idiopathic (n = 4) or heritable PAH (n = 4), PAH associated with congenital heart disease (n = 2), pulmonary veno-occlusive disease (n<

SUBMITTER: Jack T 

PROVIDER: S-EPMC10333590 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature