Transcriptome-based identification and functional characterization of iridoid synthase involved in monotropein biosynthesis in blueberry.

ABSTRACT: Blueberries (Vaccinium spp.) are well known for their nutritional quality, and recent work has shown that Vaccinium spp. also produce iridoids, which are specialized metabolites with potent health-promoting benefits. The iridoid glycoside monotropein, which has anti-inflammatory and antinociceptive activities, has been detected in several wild blueberry species but in only a few cultivated highbush blueberry cultivars. How monotropein is produced in blueberry and the genes involved in its biosynthesis remain to be elucidated. Using a monotropein-positive (M+) and monotropein-negative (M-) cultivar of blueberry, we employed transcriptomics and comparative genomics to identify candidate genes in the blueberry iridoid biosynthetic pathway. Orthology analysis was completed using

SUBMITTER: Lawas LMF 

PROVIDER: S-EPMC10333835 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature