Skeletal ¹⁸F-PSMA-1007 uptake in prostate cancer patients.

ABSTRACT:

Background/objectives

Accurate and uniform interpretation and reporting of metastatic prostate cancer (PCa) lesions on prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) are indispensable. ¹⁸F-PSMA-1007 is increasingly used because of its favorable imaging characteristics. However, increased non-specific skeletal uptake may be an important pitfall of this radioligand. Therefore, we aimed to assess the interobserver variation in reporting skeletal ¹⁸F-PSMA-1007 uptake on PET/CT.

Design/methods

In total, 33 ¹⁸F-PSMA-1007 PET/CT scans of 21 patients with primary PCa and 12 patients with biochemical recurrence were included, and a total of 85 skeletal lesions were evaluated by three independent obs

SUBMITTER: Janssen J 

PROVIDER: S-EPMC10333984 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature