Pregnancy and delivery in patients with Charcot-Marie-Tooth disease and related disorders.

ABSTRACT:

Background

Charcot-Marie-Tooth disease is the most common inherited peripheral neuropathy and many patients with Charcot-Marie-Tooth are women of childbearing age. Guidelines for managing pregnancy in Charcot-Marie-Tooth are lacking.

Aims

To assess the impact of pregnancy on Charcot-Marie-Tooth and how Charcot-Marie-Tooth affects pregnancy, delivery and postnatal care.

Methods

A retrospective questionnaire exploring disease course during pregnancy, delivery, pregnancy complications, anaesthetic management and puerperium was administered to 92 patients with Charcot-Marie-Tooth and related disorders.

Results

Worsening of Charcot-Marie-Tooth symptoms were reported in 37% of pregnant patients which resolved after delivery in half of the patients. No significant inc

SUBMITTER: Skorupinska M 

PROVIDER: S-EPMC10334032 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature