Bladder-sparing Treatment in Patients with Bacillus Calmette-Guerin-unresponsive Non-muscle-invasive Bladder Cancer: An Analysis of Long-term Survival Outcomes.

ABSTRACT:

Background

Data for bladder-sparing treatment (BST) in bacillus Calmette-Guerin (BCG)-unresponsive non-muscle-invasive bladder cancer (NMIBC) patients report short-term outcomes limited to 1-2 yr.

Objective

To assess long-term survival outcomes of BCG-unresponsive NMIBC patients treated with BST.

Design setting and participants

BCG-unresponsive NMIBC patients diagnosed between January 2000 and September 2021 from an institutional NMIBC registry were evaluated.

Intervention

Long-term survival outcomes for patients receiving BST, early radical cystectomy (RC), and delayed RC were compared.

Outcome measurements and statistical analysis

The primary endpoints were overall survival (OS) and cancer-specific survival (CSS).

Results and limitations

In tota

SUBMITTER: Tan WS 

PROVIDER: S-EPMC10334230 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature