Test-retest repeatability of ADC in prostate using the multi b-Value VERDICT acquisition.

ABSTRACT:

Purpose

VERDICT (Vascular, Extracellular, Restricted Diffusion for Cytometry in Tumours) MRI is a multi b-value, variable diffusion time DWI sequence that allows generation of ADC maps from different b-value and diffusion time combinations. The aim was to assess precision of prostate ADC measurements from varying b-value combinations using VERDICT and determine which protocol provides the most repeatable ADC.

Materials and methods

Forty-one men (median age: 67.7 years) from a prior prospective VERDICT study (April 2016-October 2017) were analysed retrospectively. Men who were suspected of prostate cancer and scanned twice using VERDICT were included. ADC maps were formed using 5b-value combinations and the within-subject standard deviations (wSD) were calculated per ADC map.

SUBMITTER: Rogers HJ 

PROVIDER: S-EPMC10334409 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature