Re-irradiation for local primary-recurrence esophageal squamous cell carcinoma treated with IMRT/VMAT.

ABSTRACT:

Purpose

Local primary-recurrence of esophageal squamous cell carcinoma (ESCC) after definitive treatment has the potential for increasing overall survival with re-irradiation (Re-RT), especially with advanced technique. This study aimed to evaluate the efficacy and toxicities of Re-RT using intensity-modulated radiotherapy (IMRT)/volumetric modulated arc therapy (VMAT) for local primary-recurrence of ESCC.

Materials and methods

A total of 130 ESCC patients with local primary-recurrence from Xijing hospital between 2008 and 2021 were enrolled and 30 patients underwent IMRT/VMAT based salvage Re-RT. Cox regression analysis was used to analyze the prognostic factors for overall survival (OS) and after recurrence survival (ARS). The toxicities of 30 patients receiving Re-RT were

SUBMITTER: Xiang G 

PROVIDER: S-EPMC10334638 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature