U-shaped association of serum magnesium with mild cognitive impairment among hemodialysis patients: a multicenter study.

ABSTRACT:

Background

The optimal serum magnesium level of patients undergoing hemodialysis (HD) with cognitive impairment is still unclear. This study aimed to evaluate the association between serum magnesium levels and mild cognitive impairment among HD patients.

Methods

This was a multicenter observational study. Patients undergoing hemodialysis from 22 dialysis centers in Guizhou Province, China were recruited into the study. HD patients were divided into five groups according to serum magnesium quintile. Cognitive function was measured with Mini Mental State Examination. The outcome was an incident mild cognitive impairment (MCI). Multivariate logistic regression analysis, restricted cubic spline and subgroup analysis were applied to explore the association of serum magnesium leve

SUBMITTER: Yang Y 

PROVIDER: S-EPMC10334860 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature