Effect of bariatric surgery on NAFLD/NASH: a single-centre observational prospective cohort study.

ABSTRACT:

Introduction

The prevalence of non-alcoholic fatty liver disease (NAFLD) ranges from 25% in the general population to 90% in patients with obesity scheduled for bariatric surgery. NAFLD can progress towards non-alcoholic steatohepatitis (NASH) associated with complications such as cirrhosis, hepatocellular carcinoma and cardiovascular disease. To date, losing weight and lifestyle modifications are the best known treatments for NASH. Bariatric surgery significantly improves NAFLD/NASH in the short term. However, the extent of this improvement is not yet clear and long-term data on the natural course of NAFLD/NASH after bariatric surgery are lacking. The factors involved in NAFLD/NASH regression after bariatric surgery have not been elucidated.

Methods and analysis

This is an

SUBMITTER: Theel WB 

PROVIDER: S-EPMC10335561 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature