Metabolic obesity phenotypes and obesity-related cancer risk in the National Health and Nutrition Examination Survey.

ABSTRACT:

Introduction

Body mass index (BMI) fails to identify up to one-third of normal weight individuals with metabolic dysfunction who may be at increased risk of obesity-related cancer (ORC). Metabolic obesity phenotypes, an alternate metric to assess metabolic dysfunction with or without obesity, were evaluated for association with ORC risk.

Methods

National Health and Nutrition Examination Survey participants from 1999 to 2018 (N = 19,500) were categorized into phenotypes according to the metabolic syndrome (MetS) criteria and BMI: metabolically healthy normal weight (MHNW), metabolically unhealthy normal weight (MUNW), metabolically healthy overweight/obese (MHO) and metabolically unhealthy overweight/obese (MUO). Adjusted multivariable logistic regression models were used to

SUBMITTER: Winn M 

PROVIDER: S-EPMC10335619 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature