A single-cell atlas of the sexually dimorphic Drosophila foreleg and its sensory organs during development.

ABSTRACT: To respond to the world around them, animals rely on the input of a network of sensory organs distributed throughout the body. Distinct classes of sensory organs are specialized for the detection of specific stimuli such as strain, pressure, or taste. The features that underlie this specialization relate both to the neurons that innervate sensory organs and the accessory cells they comprise. To understand the genetic basis of this diversity of cell types, both within and between sensory organs, we performed single-cell RNA sequencing on the first tarsal segment of the male Drosophila melanogaster foreleg during pupal development. This tissue displays a wide variety of functionally and structurally distinct sensory organs, including campaniform sensilla, mechanosensory bristles, and chemose

SUBMITTER: Hopkins BR 

PROVIDER: S-EPMC10335707 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature