Cortical structural and functional coupling during development and implications for attention deficit hyperactivity disorder.

ABSTRACT: Functional connectivity is scaffolded by the structural connections of the brain. Disruptions of either structural or functional connectivity can lead to deficits in cognitive functions and increase the risk for neurodevelopmental disorders such as attention deficit hyperactivity disorder (ADHD). To date, very little research has examined the association between structural and functional connectivity in typical development, while no studies have attempted to understand the development of structure-function coupling in children with ADHD. 175 individuals (84 typically developing children and 91 children with ADHD) participated in a longitudinal neuroimaging study with up to three waves. In total, we collected 278 observations between the ages 9 and 14 (139 each in typically developing contr

SUBMITTER: Soman SM 

PROVIDER: S-EPMC10336084 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature