Aerobic exercise training and gut microbiome-associated metabolic shifts in women with overweight: a multi-omic study.

ABSTRACT: Physical activity is essential in weight management, improves overall health, and mitigates obesity-related risk markers. Besides inducing changes in systemic metabolism, habitual exercise may improve gut's microbial diversity and increase the abundance of beneficial taxa in a correlated fashion. Since there is a lack of integrative omics studies on exercise and overweight populations, we studied the metabolomes and gut microbiota associated with programmed exercise in obese individuals. We measured the serum and fecal metabolites of 17 adult women with overweight during a 6-week endurance exercise program. Further, we integrated the exercise-responsive metabolites with variations in the gut microbiome and cardiorespiratory parameters. We found clear correlation with several serum and feca

SUBMITTER: Hintikka JE 

PROVIDER: S-EPMC10336137 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature