Long-term survival with sickle cell disease: a nationwide cohort study of Medicare and Medicaid beneficiaries.

ABSTRACT: To our knowledge, we report the first population-based period life table, the expected lifetime survival for Medicare and Medicaid beneficiaries with sickle cell disease (SCD), and the disparities in survival by insurance types in the United States. We constructed a retrospective cohort of individuals with diagnosed SCD receiving common care (any real-world patterns of care except transplant) based on nationwide Medicare and Medicaid claim data (2008-2016), covering beneficiaries in all 50 states. We analyzed lifetime survival probabilities using Kaplan-Meier curves and projected life expectancies at various ages for all, stratified by sex and insurance types. Our analysis included 94 616 individuals with SCD that have not undergone any transplant. Life expectancy at birth was 52.6 years (

SUBMITTER: Jiao B 

PROVIDER: S-EPMC10336259 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature