Partially hydrolyzed guar gum suppresses the progression of pulmonary arterial hypertension in a SU5416/hypoxia rat model.

ABSTRACT: This study investigated the effects of partially hydrolyzed guar gum (PHGG) on the development of pulmonary arterial hypertension using a SU5416/hypoxia rat model. Our results demonstrated that PHGG treatment suppressed the development of pulmonary hypertension and vascular remodeling with an altered gut microbiota composition.

SUBMITTER: Sanada TJ 

PROVIDER: S-EPMC10336776 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature