Association Between Long-Term Exposure to Fine Particulate Matter Constituents and Progression of Cerebral Blood Flow Velocity in Beijing: Modifying Effect of Greenness.

ABSTRACT: Few studies have explored the effects of fine particulate matter (PM_2.5) and its constituents on the progression of cerebral blood flow velocity (BFV) and the potential modifying role of greenness. In this study, we investigated the association of PM_2.5 and its constituents, including sulfate (SO₄ ^2-), nitrate (NO₃ ^-), ammonium (NH₄ ⁺), organic matter (OM), and black carbon (BC), with the progression of BFV in the middle cerebral artery. Participants from the Beijing Health Management Cohort who underwent at least two transcranial Doppler sonography examinations during 2015-2020 were recruited. BFV change and BFV change rate were used to define the progression of cerebral BFV. Linear mixed effects model

SUBMITTER: Xu Z 

PROVIDER: S-EPMC10337285 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature