Malignancy rates in Crohn's disease patients with perianal fistula: A German retrospective cohort study.

ABSTRACT:

Background

Patients with inflammatory bowel disease are at increased risk of colorectal and extra-intestinal cancer. However, the overall cancer risk in patients with Crohn's disease (CD) with perianal fistulas (PF) (CPF) and those with CD without PF (non-PF CD) is unclear.

Objective

To describe the prevalence and incidence of cancer in patients with CPF and non-PF CD, and to estimate incidence rate ratio (IRR) of cancer between CPF and non-PF CD groups.

Methods

A retrospective cohort study was conducted using the German InGef (Institute for Applied Health Research Berlin) research database. Patients with a CD record and PF from 1 January 2013 to 31 December 2014 were identified and followed up from 1 January 2015 until the first occurrence of cancer, end of health in

SUBMITTER: Podmore B 

PROVIDER: S-EPMC10337731 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature