Efficacy of preoperative chemoradiotherapy in patients with cT2N0 distal rectal cancer.

ABSTRACT:

Purpose

This study was designed to determine the feasibility of preoperative chemoradiotherapy (PCRT) in patients with clinical T2N0 distal rectal cancer.

Methods

Patients who underwent surgery for clinical T2N0 distal rectal cancer between January 2008 and December 2016 were included. Patients were divided into PCRT and non-PCRT groups. Non-PCRT patients underwent radical resection or local excision (LE) according to the surgeon's decision, and PCRT patients underwent surgery according to the response to PCRT. Patients received 50.0 to 50.4 gray of preoperative radiotherapy with concurrent chemotherapy.

Results

Of 127 patients enrolled, 46 underwent PCRT and 81 did not. The mean distance of lesions from the anal verge was lower in the PCRT group (P=0.004). The most f

SUBMITTER: Park MY 

PROVIDER: S-EPMC10338167 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature