Cumulative exposure to metabolic syndrome increases thyroid cancer risk in young adults: a population-based cohort study.

ABSTRACT:

Background/aims

A re-increasing trend of thyroid cancer since 2015 has been observed despite a similar examination rate, and the incidence of thyroid cancer among young adults continues to rise.

Methods

This study used data from the Korean National Health Insurance Service. Individuals 20-39 years of age who underwent ≥ 4 health checkups from 2009-2013 were enrolled and followed throughout 2019. To quantify the metabolic burden, groups were divided by the number of diagnoses of metabolic syndrome across four consecutive health examinations.

Results

Among the study population (n = 1,204,646), 5,929 (0.5%) were diagnosed with thyroid cancer during a follow- up period of 5 years. The hazard ratio (95% confidence interval) values of thyroid cancer occurrence according to

SUBMITTER: Kim J 

PROVIDER: S-EPMC10338240 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature