Six-year experience of Australia's first dedicated cancer of unknown primary clinic.

ABSTRACT:

Background

Diagnosis and management of cancers of unknown primary (CUP) remain challenging. This study examines the referral patterns, management and outcomes of patients referred to Australia's first dedicated CUP clinic.

Methods

Retrospective medical record review was conducted for patients seen at the Peter MacCallum Cancer Centre CUP clinic between July 2014 and August 2020. Overall survival (OS) was analysed for patients with a CUP diagnosis where treatment information was available.

Results

Of 361 patients referred, fewer than half had completed diagnostic work-up at the time of referral. A diagnosis of CUP was established in 137 (38%), malignancy other than CUP in 177 (49%) and benign pathology in 36 (10%) patients. Genomic testing was successfully completed in

SUBMITTER: van Mourik A 

PROVIDER: S-EPMC10338450 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature