Antigen test swabs are comparable to nasopharyngeal swabs for sequencing of SARS-CoV-2.

ABSTRACT: Viral genomic surveillance has been integral in the global response to the SARS-CoV-2 pandemic. Surveillance efforts rely on the availability of representative clinical specimens from ongoing testing activities. However, testing practices have recently shifted due to the widespread availability and use of rapid antigen tests, which could lead to gaps in future monitoring efforts. As such, genomic surveillance strategies must adapt to include laboratory workflows that are robust to sample type. To that end, we compare the results of RT-qPCR and viral genome sequencing using samples from positive BinaxNOW COVID-19 Antigen Card swabs (N = 555) to those obtained from nasopharyngeal (NP) swabs used for nucleic acid amplification testing (N = 135). We show that swabs obtained from antigen cards

SUBMITTER: Hassouneh SA 

PROVIDER: S-EPMC10338537 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature