Molecular system for an exponentially fast growing programmable synthetic polymer.

ABSTRACT: In this paper, we demonstrate a molecular system for the first active self-assembly linear DNA polymer that exhibits programmable molecular exponential growth in real time, also the first to implement "internal" parallel insertion that does not rely on adding successive layers to "external" edges for growth. Approaches like this can produce enhanced exponential growth behavior that is less limited by volume and external surface interference, for an early step toward efficiently building two and three dimensional shapes in logarithmic time. We experimentally demonstrate the division of these polymers via the addition of a single DNA complex that competes with the insertion mechanism and results in the exponential growth of a population of polymers per unit time. In the supplementary materia

SUBMITTER: Dabby N 

PROVIDER: S-EPMC10338630 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature