Association between adverse childhood experiences and later-life allostatic load in UK Biobank female participants.

ABSTRACT:

Background

Adverse childhood experiences during key developmental periods have been shown to impact long-term health outcomes. Adverse childhood experiences may include psychological, physical, or sexual abuse; neglect; or socioeconomic factors. Adverse childhood experiences are linked with an increase in poor health behavior such as smoking and alcohol consumption, and may also influence epigenetic changes, inflammatory response, metabolic changes, and allostatic load.

Objective

We sought to explore associations between adverse childhood experiences and allostatic load in adult female participants in the UK Biobank.

Design

The UK Biobank is a multisite cohort study established to capture lifestyle, environment, exposure, health history, and genotype data on individua

SUBMITTER: Jakubowski D 

PROVIDER: S-EPMC10338729 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature