RTMS treatment for abrogating intracerebral hemorrhage-induced brain parenchymal metabolite clearance dysfunction in male mice by regulating intracranial lymphatic drainage.

ABSTRACT:

Background

The discovery of the glymphatic system and meningeal lymphatic vessels challenged the traditional view regarding the lack of a lymphatic system in the central nervous system. It is now known that the intracranial lymphatic system plays an important role in fluid transport, macromolecule uptake, and immune cell trafficking. Studies have also shown that the function of the intracranial lymphatic system is significantly associated with neurological diseases; for example, an impaired intracranial lymphatic system can lead to Tau deposition and an increased lymphocyte count in the brain tissue of mice with subarachnoid hemorrhage.

Methods

In this study, we assessed the changes in the intracranial lymphatic system after intracerebral hemorrhage and the regulatory effect

SUBMITTER: Liu Y 

PROVIDER: S-EPMC10338767 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature