Impact of new-onset and preexisting neurological disorders in COVID-19 patients.

ABSTRACT:

Background and purpose

Coronavirus disease (COVID-19) is still considered a global pandemic. The prognosis of COVID-19 patients varies greatly. We aimed to assess the impact of preexisting, chronic neurological diseases (CNDs) and new-onset acute neurological complications (ANCs) on the disease course, its complications, and outcomes.

Methods

We conducted a monocentric retrospective analysis from all hospitalized COVID-19 patients between May 1, 2020 and January 31, 2021. Employing multivariable logistic regression models, we explored the association of CNDs and ANCs separately with hospital mortality and functional outcome.

Results

A total of 250 among 709 patients with COVID-19 had CNDs. We found a 2.0 times higher chance of death (95% confidence interval [CI]: 1.37

SUBMITTER: Lindemann S 

PROVIDER: S-EPMC10338781 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature