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Altered brain activity in patients with end-stage renal disease: A meta-analysis of resting-state functional imaging.


ABSTRACT:

Introduction

Previous studies have revealed abnormal resting-state brain activity in patients with end-stage renal disease (ESRD); however, the results are inconsistent. Thus, we conducted a coordinate-based meta-analysis of whole-brain resting-state functional neuroimaging studies in ESRD to identify the most consistent neural activity alterations in ESRD patients and explore their relation to serological indicators.

Methods

A comprehensive literature search strategy was applied to select pertinent studies up to December 2022 in PubMed, Web of Science, and Embase databases. Voxel-wise meta-analysis was conducted via the latest meta-analytic algorithm, seed-based d mapping with permutation of subject images software. Meta-regression analyses were also conducted to explore th

SUBMITTER: Song W 

PROVIDER: S-EPMC10338797 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature