Response to Biologic Drugs in Patients With Rheumatoid Arthritis and Antidrug Antibodies.

ABSTRACT:

Importance

There are conflicting data on the association of antidrug antibodies with response to biologic disease-modifying antirheumatic drugs (bDMARDs) in rheumatoid arthritis (RA).

Objective

To analyze the association of antidrug antibodies with response to treatment for RA.

Design, setting, and participants

This cohort study analyzed data from the ABI-RA (Anti-Biopharmaceutical Immunization: Prediction and Analysis of Clinical Relevance to Minimize the Risk of Immunization in Rheumatoid Arthritis Patients) multicentric, open, prospective study of patients with RA from 27 recruiting centers in 4 European countries (France, Italy, the Netherlands, and the UK). Eligible patients were 18 years or older, had RA diagnosis, and were initiating a new bDMARD. Recruitment s

SUBMITTER: Bitoun S 

PROVIDER: S-EPMC10339150 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature