Stereotactic Body Radiation Therapy in Gynecologic Oligometastases: An Effective but Underutilized Approach.

ABSTRACT: Historically, the role of radiation in gynecological metastatic disease involved palliation for pain or bleeding. Stereotactic Body Radiation Therapy (SBRT) has shown survival benefits in oligometastatic disease from varying primary histologies in recent randomized trials. However, gynecologic primary oligometastases have been underrepresented in these trials. Recent studies across gynecological malignancy types have similarly shown favorable outcomes and acceptable toxicities from treating recurrent or oligometastatic gynecologic cancer (ROMGC) patients with definitive radiation therapy. The largest body of literature reported on the use of SBRT in ovarian cancer, which was found to be an effective option, especially in the setting of chemo-resistant disease. Despite the encouraging outco

SUBMITTER: Sherwani Z 

PROVIDER: S-EPMC10340138 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature