Vitamin E and Its Molecular Effects in Experimental Models of Neurodegenerative Diseases.

ABSTRACT: With the advancement of in vivo studies and clinical trials, the pathogenesis of neurodegenerative diseases has been better understood. However, gaps still need to be better elucidated, which justifies the publication of reviews that explore the mechanisms related to the development of these diseases. Studies show that vitamin E supplementation can protect neurons from the damage caused by oxidative stress, with a positive impact on the prevention and progression of neurodegenerative diseases. Thus, this review aims to summarize the scientific evidence of the effects of vitamin E supplementation on neuroprotection and on neurodegeneration markers in experimental models. A search for studies published between 2000 and 2023 was carried out in the PubMed, Web of Science, Virtual Health Librar

SUBMITTER: da Cunha Germano BC 

PROVIDER: S-EPMC10342514 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature