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Recent Advances in Sodium Magnetic Resonance Imaging and Its Future Role in Kidney Disease.

ABSTRACT: Sodium imbalance is a hallmark of chronic kidney disease (CKD). Excess tissue sodium in CKD is associated with hypertension, inflammation, and cardiorenal disease. Sodium magnetic resonance imaging (²³Na MRI) has been increasingly utilized in CKD clinical trials especially in the past few years. These studies have demonstrated the association of excess sodium tissue accumulation with declining renal function across whole CKD spectrum (early- to end-stage), biomarkers of systemic inflammation, and cardiovascular dysfunction. In this article, we review recent advances of ²³Na MRI in CKD and discuss its future role with a focus on the skin, the heart, and the kidney itself.

SUBMITTER: Akbari A

PROVIDER: S-EPMC10342976 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature

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Recent Advances in Sodium Magnetic Resonance Imaging and Its Future Role in Kidney Disease.

Akbari Alireza A McIntyre Christopher W CW

Journal of clinical medicine 20230629 13

Sodium imbalance is a hallmark of chronic kidney disease (CKD). Excess tissue sodium in CKD is associated with hypertension, inflammation, and cardiorenal disease. Sodium magnetic resonance imaging (<sup>23</sup>Na MRI) has been increasingly utilized in CKD clinical trials especially in the past few years. These studies have demonstrated the association of excess sodium tissue accumulation with declining renal function across whole CKD spectrum (early- to end-stage), biomarkers of systemic infla ...[more]

PMID: 37445416

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Recent Advances in Sodium Magnetic Resonance Imaging and Its Future Role in Kidney Disease.

Publications

Recent Advances in Sodium Magnetic Resonance Imaging and Its Future Role in Kidney Disease.

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