Methionine metabolism and endocrine function of the pituitary gland in patients with suprasellar germinoma.

ABSTRACT:

Purpose

The aim of this study was to investigate the association between methionine (MET) metabolism and endocrine function of the pituitary gland in patients with suprasellar region tumor.

Materials and methods

Twenty patients with intracranial germinoma were included in this study. Initial staging and all surveillance MET PET/CT scans and comparable serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), and thyroid stimulating hormone (TSH) were analyzed. The patients were divided into two groups according to tumor location, with tumors in the suprasellar region (condition) or not (control). MET uptake of the pituitary gland (i.e., SUVR [standardized uptake value ratio]) and levels of FSH, LH, TSH were compared in the condition and control groups and

SUBMITTER: Lee H 

PROVIDER: S-EPMC10343025 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature