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Plant Sterols and Plant Stanols in Cholesterol Management and Cardiovascular Prevention.


ABSTRACT: Atherosclerotic cardiovascular disease (ASCVD) remains the major mortality cause in developed countries with hypercholesterolaemia being one of the primary modifiable causes. Lifestyle intervention constitutes the first step in cholesterol management and includes dietary modifications along with the use of functional foods and supplements. Functional foods enriched with plant sterols/stanols have become the most widely used nonprescription cholesterol-lowering approach, despite the lack of randomized trials investigating their long-term safety and cardiovascular efficacy. The cholesterol-lowering effect of plant-sterol supplementation is well-established and a potential beneficial impact on other lipoproteins and glucose homeostasis has been described. Nevertheless, experimental and human

SUBMITTER: Barkas F 

PROVIDER: S-EPMC10343346 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature