Sex differences in cerebral venous sinus thrombosis after adenoviral vaccination against COVID-19.

ABSTRACT:

Introduction

Cerebral venous sinus thrombosis associated with vaccine-induced immune thrombotic thrombocytopenia (CVST-VITT) is a severe disease with high mortality. There are few data on sex differences in CVST-VITT. The aim of our study was to investigate the differences in presentation, treatment, clinical course, complications, and outcome of CVST-VITT between women and men.

Patients and methods

We used data from an ongoing international registry on CVST-VITT. VITT was diagnosed according to the Pavord criteria. We compared the characteristics of CVST-VITT in women and men.

Results

Of 133 patients with possible, probable, or definite CVST-VITT, 102 (77%) were women. Women were slightly younger [median age 42 (IQR 28-54) vs 45 (28-56)], presented more often with co

SUBMITTER: Scutelnic A 

PROVIDER: S-EPMC10345391 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature