Antibiotic resistance profile of Helicobacter pylori to 14 antibiotics: a multicenter study in Fujian, China.

ABSTRACT:

Background and aim

Efficacy of Helicobacter pylori (H. pylori) eradication is related to the local antimicrobial resistance epidemiology. We aimed to investigate the antibiotic resistance of H. pylori in Fujian, China.

Methods

H. pylori-infected patients in four centers were enrolled in the study from Oct 2019 to Jan 2022. The bacteria were isolated, cultured and identified from the biopsy of patients' gastric mucosa samples. Antimicrobial susceptibility testing was performed by a modified broth microdilution method for H. pylori to seven guideline-recommended antibiotics and seven potential choices for H. pylori eradication.

Results

A total of 205 H. pylori strains were isolated. The resistance rates of amoxicillin (AM

SUBMITTER: Huang X 

PROVIDER: S-EPMC10348307 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature