Mechanisms underlying the anti-aging activity of bergamot (Citrus bergamia) extract in human red blood cells.

ABSTRACT: Introduction: Aging is a process characterised by a decline in physiological functions. Reactive species play a crucial role in the aging rate. Due to the close relationship between aging and oxidative stress, functional foods rich in phytochemicals are excellent candidates to neutralise age-related changes. Aim: This investigation aims to verify the potential protective role of bergamot (Citrus bergamia, Femminello cultivar) peel and juice extract in a model of aging represented by human red blood cells (RBCs) exposed to D-Galactose (DGal). Methods: Bergamot peel and juice extracts were subjected to RP-HPLC/PDA/MS for determination of their composition in bioactive compounds. Markers of oxidative stress, including ROS production, thiobarbituric acid reac

SUBMITTER: Remigante A 

PROVIDER: S-EPMC10348362 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature