Autoimmune Disease-Related Hub Genes are Potential Biomarkers and Associated with Immune Microenvironment in Endometriosis.

ABSTRACT:

Background

Endometriosis, a common gynecological condition, can cause symptoms such as dysmenorrhea, infertility, and abnormal bleeding, which can negatively affect a woman's quality of life. In the current study, the pathophysiological mechanisms of endometriosis are unknown, but this study suggests that endometriosis is associated with dysregulation of the autoimmune system. This study identify hub genes involved in the prevalence, identification and diagnostic value of endometriosis and autoimmune diseases, and explore the central genes and immune infiltrates, the diagnosis of endometriosis provides a new sight of thinking about diagnosis and treatment.

Methods and results

The relevant datasets for endometriosis GSE141549, GSE7305 and autoimmune disease-related genes (AID

SUBMITTER: Yang YT 

PROVIDER: S-EPMC10348380 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature