Investigation into relationships between design parameters and mechanical properties of 3D printed PCL/nHAp bone scaffolds.

ABSTRACT:

Background

Scaffolds are of great importance in tissue engineering applications as they provide a mechanically supportive environment for cellular activity, which is particularly necessary for hard tissues such as bone. Notably, the mechanical properties of a scaffold vary with differing design parameters such as those related to scaffold height and internal structure. Thus, the present study aimed to explore the relationship between design parameters and mechanical properties of composite polycaprolactone (PCL) and nano-hydroxyapatite (nHAp) scaffolds fabricated by three-dimensional (3D) printing.

Methods

We designed and printed scaffolds with different internal structures (lattice and staggered) and varying heights (4, 6, 8 and 10 layers), and consistent porosity (50%) for

SUBMITTER: Yazdanpanah Z 

PROVIDER: S-EPMC10348542 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature