Metabolic response of intestinal microbiota to guar gum consumption.

ABSTRACT:

Background

Guar gum is used extensively as a thickening agent in food, but it remains uncertain whether and to what extent it is fermented by colonic microbiota and whether it has microbiota modulatory properties.

Aim

To determine the metabolic response of intestinal microbiota to guar gum consumption, specifically, the extent of initial fermentation and subsequent adaptation.

Methods

Single-center, single arm, open label, proof-of-concept study testing the effect of guar gum on microbiota metabolism and adaptation. Healthy male subjects (n = 12) were administered gum guar (8 g/day) for 18 days. Outcomes were measured before, at initial and late administration: (a) anal gas evacuations (number/day); (b) digestive sensations (daily scales); and (c) fecal gut mic

SUBMITTER: Barber C 

PROVIDER: S-EPMC10349393 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature