The diagnostic significance of circulating miRNAs and metabolite profiling in early prediction of breast cancer in Egyptian women.

ABSTRACT:

Objective

Breast cancer (BC) is one of the most commonly diagnosed solid malignancies in women worldwide.

Purpose

Finding new non-invasive circulating diagnostic biomarkers will facilitate the early prediction of BC and provide valuable insight into disease progression and response to therapy using a safe and more accessible approach available every inspection time. Therefore, our present study aimed to investigate expression patterns of potentially circulating biomarkers that can differentiate well between benign, malignant, and healthy subjects.

Methods

To achieve our target, quantitative analyses were performed for some circulating biomarkers which have a role in the proliferation and tumor growth, as well as, glutamic acid, and human epidermal growth receptor 2 (H

SUBMITTER: El-Toukhy SE 

PROVIDER: S-EPMC10349790 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature