Divergence in the Saccharomyces species' heat shock response is indicative of their thermal tolerance.

ABSTRACT: The Saccharomyces species have diverged in their thermal growth profile. Both S. cerevisiae and S. paradoxus grow at temperatures well above the maximum growth temperature of S. kudriavzevii and S. uvarum, but grow more poorly at lower temperatures. In response to thermal shifts, organisms activate a stress response that includes heat shock proteins involved in protein homeostasis and acquisition of thermal tolerance. To determine whether Saccharomyces species have diverged in their response to temperature we measured changes in gene expression in response to a 12°C increase or decrease in temperature for four Saccharomyces species and their six pairwise hybrids. To ensure coverage of subtelomeric gene families we sequenced, assembled and an

SUBMITTER: Fay JC 

PROVIDER: S-EPMC10349932 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature