Photoinduced bidirectional switching in lipid membranes containing azobenzene glycolipids.

ABSTRACT: Following the reaction of biological membranes to external stimuli reveals fundamental insights into cellular function. Here, self-assembled lipid monolayers act as model membranes containing photoswitchable azobenzene glycolipids for investigating structural response during isomerization by combining Langmuir isotherms with X-ray scattering. Controlled in-situ trans/cis photoswitching of the azobenzene N = N double bond alters the DPPC monolayer structure, causing reproducible changes in surface pressure and layer thickness, indicating monolayer reorientation. Interestingly, for monolayers containing azobenzene glycolipids, along with the expected DPPC phase transitions an additional discontinuity is observed. The associated reorintation represents a crossover point, with the surface pres

SUBMITTER: Warias JE 

PROVIDER: S-EPMC10350456 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature