Impairments to the multisensory integration brain regions during migraine chronification: correlation with the vestibular dysfunction.

ABSTRACT:

Objectives

Migraine is often combined with vestibular dysfunction, particularly in patients with chronic migraine (CM). However, the pathogenesis of migraine chronification leading to vestibular dysfunction is not fully understood. The current study investigated whether structural or functional impairments to the brain during migraine chronification could be associated with vestibular dysfunction development.

Methods

The eligible participants underwent clinical assessment and magnetic resonance imaging (MRI) scans. Voxel-based morphometry (VBM) determined structural impairment by evaluating alterations in gray matter volume (GMV). Functional impairment was assessed by the mean amplitude of low-frequency fluctuation (mALFF). Furthermore, the resting-state functional connectiv

SUBMITTER: Dong L 

PROVIDER: S-EPMC10350528 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature