Response to endobronchial valve treatment: it's all about the target lobe.

ABSTRACT:

Background

Bronchoscopic lung volume reduction using endobronchial valves (EBV) has been shown to be beneficial for severe emphysema patients. The most important predictor of treatment response is absence of collateral ventilation between the treatment target and ipsilateral lobe. However, there are still a substantial number of nonresponders and it would be useful to improve the pre-treatment identification of responders. Presumably, predictors of response will be multifactorial, and therefore our aim was to explore whether we can identify response groups using a cluster analysis.

Methods

At baseline and 1 year follow-up, pulmonary function, exercise capacity and quality of life were measured. A quantitative chest computed tomography scan analysis was performed at baseline

SUBMITTER: Hartman JE 

PROVIDER: S-EPMC10350677 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature