High sensitivity troponin-I threshold to predict perioperative myocardial infarction.

ABSTRACT:

Background

High-sensitivity Troponin I (hs-cTnI) has largely replaced conventional troponin assays in an effort to improve detection of myocardial infarction. However, the mean displacement of hs-cTnI following coronary artery bypass graft (CABG) and the optimal threshold to detect perioperative myocardial infarction (MI) is unclear. Our objective is to describe mean hs-cTnI values at 6-12 h post-CABG and to determine the highest specificity while maintaining 100% sensitivity hs-cTnI cut-off values for diagnosis of perioperative or type-5 MI.

Methods

Between 2016 and 2018, 374 patients underwent non-emergent, isolated CABG. Pre-operative and 6 h post-operative hs-cTnI values were recorded as well as ECG, echocardiographic and angiographic data.

Results

Of 374 patients

SUBMITTER: Friedman T 

PROVIDER: S-EPMC10351123 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature