Isolation and identification of active ingredients and biological activity of Dioscorea nipponica Makino.

ABSTRACT: This study reported the isolation and identification of bioactive compounds from Dioscorea nipponica Makino, a plant used in traditional medicine for various ailments. Nine compounds were isolated, including a new compound named as diosniposide E, which was elucidated by analyzing its ¹H-NMR, ¹³C-NMR, DEPT, COSY, HMBC and MS data and comparing them with data available in literature. The other eight compounds were identified as known compounds. Theoretical calculations of energy and the generation of a molecular electrostatic potential surface map were employed to assess the antioxidant capacity of nine compounds, the calculation results exhibited that compounds 5 and 6 had strong antioxidant capacities. To further evaluate the antioxidant activities of the investigate

SUBMITTER: Xia G 

PROVIDER: S-EPMC10351190 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature