Trajectories of depressive symptoms in older adults and associated health outcomes.

ABSTRACT: With the progressive aging of the world's population, prolongation of a healthy lifespan in old age has become a medical research priority. The presence of depressive symptoms in later life is associated with poor health prognosis and increased mortality^1,2. Here we explore distinct trajectories of depressive symptoms in later life and their association with several health-related outcomes in 19,110 older individuals followed for a median of 4.7 years. Using a latent class, mixed-modeling approach we identified four distinct trajectories of depressive symptoms with scoring patterns of consistently low, moderate, emerging and persistently high. Compared to those with minimal depressive symptoms, membership of any other class was associated with specific patterns of baseline socio

SUBMITTER: Agustini B 

PROVIDER: S-EPMC10351394 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature