Predictive Factors for Renal Response in Lupus Nephritis: A Single-center Prospective Cohort Study.

ABSTRACT:

Objective

To identify the predictive factors for renal response in patients with lupus nephritis (LN).

Methods

Patients and data were extracted from a prospective systemic lupus erythematosus cohort in Korea, in which clinical data were collected at 0, 3, 6, and 12 months after induction therapy. Treatment response of LN were evaluated as a complete response (CR), partial response (PR), or non-response (NR) at 3, 6, and 12 months, respectively. Predictive factors for CR at 6 months were evaluated using multivariable Poisson regression analysis.

Results

A total of 75 patients with LN who underwent biopsy was enrolled. The mean age at diagnosis of LN was 28.9±9.7 years, and 68 (90.7%) were female. The frequencies of classes III, IV, III+V, IV+V, and V were 20.0%, 44.0%,

SUBMITTER: Park DJ 

PROVIDER: S-EPMC10351413 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature